- Body system
- Neurology
- Brand names
- Keppra, Spritam, Elepsia XR
What is Levetiracetam used for?
- Focal (partial) seizures
- Myoclonic seizures
- Primary generalized tonic-clonic seizures
- Seizure prevention after brain injury (off-label)
How Levetiracetam works
Antiepileptic that binds the synaptic vesicle protein SV2A and reduces abnormal neuron firing.
Common side effects
- Drowsiness and fatigue
- Dizziness
- Irritability and mood changes
Report right away
- Aggression, depression, anxiety or suicidal thoughts
- Rash or skin blistering
- Seizures that worsen
Nursing considerations for Levetiracetam
- Doses are adjusted for kidney function.
- Routine blood levels are not needed.
- Assess mood and behavior: like all antiepileptic drugs, it carries a warning for suicidal thoughts.
Patient teaching
- Do not stop it suddenly: seizures can return.
- Do not drive until you know how it affects you and your provider says it is safe.
This card does not list doses. Use the prescriber's order, the product label and a current drug reference for dosing, and follow your facility's policies.
Anticonvulsants (antiepileptic drugs) practice questions
NCLEX-style questions on the class Levetiracetam belongs to.
3 questions. Choose an answer to see the rationale.
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Which IV solution is compatible with phenytoin?
Show answer
Answer B: 0.9% sodium chloride Phenytoin precipitates in dextrose solutions; it is mixed and flushed with normal saline only.
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A patient taking phenytoin has nystagmus, unsteady gait and slurred speech. What does the nurse suspect?
Show answer
Answer D: Phenytoin toxicity Nystagmus and ataxia are classic signs of high phenytoin levels. Check the level and notify the provider.
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What teaching point applies to every antiepileptic drug?
Show answer
Answer C: Do not stop it suddenly Abrupt withdrawal can trigger seizures, including status epilepticus.
Frequently asked questions
What is Levetiracetam used for?
Focal (partial) seizures; Myoclonic seizures; Primary generalized tonic-clonic seizures; Seizure prevention after brain injury (off-label).
What drug class is Levetiracetam?
Levetiracetam belongs to the class anticonvulsants (antiepileptic drugs). Antiepileptic that binds the synaptic vesicle protein SV2A and reduces abnormal neuron firing.
What are the nursing considerations for Levetiracetam?
Doses are adjusted for kidney function. Routine blood levels are not needed.
What should patients report while taking Levetiracetam?
aggression, depression, anxiety or suicidal thoughts; rash or skin blistering; seizures that worsen.