- Body system
- Anti-infectives
- Name stem
- -cycline
- Drug cards
- 1 in this guide
Drugs in this class
Other examples: Tetracycline, Minocycline, Tigecycline.
How tetracyclines work
Bind the 30S ribosomal subunit and block protein synthesis (bacteriostatic).
Uses
- Lyme disease and Rocky Mountain spotted fever
- Acne and rosacea
- Chlamydia
- Community-acquired pneumonia
- Anthrax and malaria prevention
Adverse effects
- Photosensitivity
- Esophagitis
- Tooth discoloration and bone effects in children under 8 and the fetus
- GI upset
- Dizziness (minocycline)
Nursing considerations
- Avoid in pregnancy and in children under 8 unless the benefit outweighs the risk.
- Separate from antacids, iron, calcium and magnesium.
Patient teaching
- Take with a full glass of water and stay upright for 30 minutes.
- Use sunscreen.
- Report severe headache or vision changes.
Tetracyclines NCLEX practice questions
Answer each question to see the rationale.
3 questions. Choose an answer to see the rationale.
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Why is doxycycline generally avoided in children younger than 8?
Show answer
Answer A: It can permanently discolor developing teeth Tetracyclines bind calcium in developing teeth and bone. Exceptions exist for serious infections such as Rocky Mountain spotted fever.
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What instruction prevents esophageal injury from doxycycline?
Show answer
Answer D: Take it with a full glass of water and stay upright for 30 minutes Tablets that lodge in the esophagus can cause ulcers.
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Which teaching applies to most tetracyclines?
Show answer
Answer C: Avoid sun exposure and use sunscreen Tetracyclines cause photosensitivity; sun protection prevents severe sunburn.
Frequently asked questions
What are tetracyclines?
Tetracyclines (the -cycline drugs) treat tick-borne illness, acne and atypical infections. Remember: upright with water, sun protection, and avoid in pregnancy and young children when possible.
How do tetracyclines work?
Bind the 30S ribosomal subunit and block protein synthesis (bacteriostatic).
What are examples of tetracyclines?
Doxycycline, Tetracycline, Minocycline and Tigecycline.
What are the nursing considerations for tetracyclines?
Avoid in pregnancy and in children under 8 unless the benefit outweighs the risk. Separate from antacids, iron, calcium and magnesium.